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ORIGINAL ARTICLECircRNAs as Potential Biomarkers in Gastrointestinal Tract Tumors: Opportunities and Challenges by Cuixia Liu, Ni Liu, Bole Cao, Zhenping Zhou, Guifeng Yang, Peng Zhou

Most digestive system tumors have poor prognoses due to the lack of specific biomarkers. Circular RNAs (circRNAs) regulate the expression of genes and play essential roles in digestive system tumorigenesis. Here we review circRNA functions in gastrointestinal tract tumors. CircRNAs are promising biomarkers for clinical applications for gastrointestinal tract tumors.

DOI: 10.7754/Clin.Lab.2017.170731